ABOUT THIS IMAGE. HAPLOSCOPE plot of variation in the lactase region of the human genome.

At each genomic location, relative frequencies of haplotype clusters are shown on a thin vertical line. Each color depicts a haplotype cluster, and the proportion of a line in a color gives the frequency of the cluster associated with the color. The long high-frequency cluster in European populations, quantified by the plot of haplotype cluster homozygosity at the lower right corner, reflects a selective sweep in the lactase region. The figure is based on the work of Jakobsson, Scholz, Scheet, et al. (Genotype, haplotype and copy-number variation in worldwide human populations; Nature 451: 998-1003, 2008).

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